CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Jagged-1 signalling is required in liver fibrogensis
DOI 10.1055/s-0030-1269508
Bibliografische Angaben
Nachweis in CareLit
Autor:innenH Weng, Y Liu, I Ilkavets, H Shen, V Zimmer, F Lammert, A Mueller, F Herweck, C Stump, PR Mertens, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background & Aims: Mutation of Jagged-1 gene, a Notch ligand, leads to Alagille syndrome. However, patients with Alagille syndrome usually do not progress into serious liver fibrosis. In the present study, we investigated the role of Jagged-1 in liver fibrogenesis. Methods: Jagged-1 expression in diseased human and mouse livers were evaluated by immunohistochemistry and Western blot. The effect of a Jagged-1 was exa…
Zitieren
Zitierempfehlung
H Weng, Y Liu, I Ilkavets, H Shen, V Zimmer, F Lammert, A Mueller, F Herweck, C Stump, PR Mertens, S Dooley (2011) Jagged-1 signalling is required in liver fibrogensis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269508
Mit CareLit weiterarbeiten