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Neoangiogenesis and nitric oxide is increased in hepatic arteries of decompensated but not compensated CCl4-cirrhotic rats, a process that can be blocked by Sorafenib

A Zipprich, M Engelhardt, B Christ, T Seufferlein, M Dollinger · Zeitschrift für Gastroenterologie · Ausgabe 01/2011

DOI 10.1055/s-0030-1269514

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Autor:innenA Zipprich, M Engelhardt, B Christ, T Seufferlein, M Dollinger
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Hepatic arteries in cirrhosis show neoangiogenesis and vasodilatation, the latter mainly as a consequence of increased nitric oxide (Zipprich et al.JHep;49: 739). It remains unclear, when these pathological changes occur during the natural history of cirrhosis, i.e. in compensated or decompensated cirrhosis, and if the multikinase-inhibitor Sorafenib has an inhibitory effect. The aim of the study was to investigate…

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Zitierempfehlung

A Zipprich, M Engelhardt, B Christ, T Seufferlein, M Dollinger (2011) Neoangiogenesis and nitric oxide is increased in hepatic arteries of decompensated but not compensated CCl4-cirrhotic rats, a process that can be blocked by Sorafenib. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269514

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