CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
MIF exerts anti-fibrotic effects in experimental liver fibrosis via CD74
DOI 10.1055/s-0030-1269517
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Autor:innenD Heinrichs, M Jung, ML Berres, A Nellen, P Schmitz, R Bucala, C Trautwein, C Weber, J Bernhagen, HE Wasmuth
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Macrophage migration inhibitory factor (MIF) has been implicated in inflammatory diseases. Chronic inflammation is a mainstay of liver fibrosis but the specific role of MIF in liver scarring has not yet been elucidated. Here we uncover an unexpected anti-fibrotic role of MIF in vivo and in vitro. Methods: Liver fibrosis was induced by CCl4 and TAA in Mif‒/‒, Cd74‒/‒ mice and wild-type mice. Fibrosis was analyz…
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Zitierempfehlung
D Heinrichs, M Jung, ML Berres, A Nellen, P Schmitz, R Bucala, C Trautwein, C Weber, J Bernhagen, HE Wasmuth (2011) MIF exerts anti-fibrotic effects in experimental liver fibrosis via CD74. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269517
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