CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The HDAC inhibitor Panobinostat induce differentiation and reduce de-differentiation in human hepatoma xenografts
DOI 10.1055/s-0030-1269519
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Nachweis in CareLit
Autor:innenB Alinger, P Di Fazio, K Quint, M Ocker, D Neureiter
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Beside proliferation and apoptosis the status of trans- or de-differentiation seems to play a key role in tumor initiation, progression or metastasizing. Inhibitors of histone deacetylases (HDACi) represent a novel therapeutic option for human cancer diseases. The aim of this study is to show the possible influence of epigenetic modifications on the differentiation mechanisms of human hepatocellular carcinoma…
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Zitierempfehlung
B Alinger, P Di Fazio, K Quint, M Ocker, D Neureiter (2011) The HDAC inhibitor Panobinostat induce differentiation and reduce de-differentiation in human hepatoma xenografts. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269519
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