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MicroRNAs are key players of the p53 pathway in hepatocellular carcinoma

MH Bender, LC Koenig, N Joschko, W Stremmel, M Müller-Schilling · Zeitschrift für Gastroenterologie · Ausgabe 01/2011

DOI 10.1055/s-0030-1269523

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Autor:innenMH Bender, LC Koenig, N Joschko, W Stremmel, M Müller-Schilling
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben

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Introduction: MicroRNAs (miR) are noncoding regulatory RNA molecules which play a role as tumor suppressors or oncogenes in nearly all types of cancer. It has been shown that microRNAs, most notably members of the miR-34 family underlie transcriptional regulation by p53. Of clinical importance a loss of miR-34a has been linked to resistance against apoptosis induced by p53-activating chemotherapeutic agents.We have…

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MH Bender, LC Koenig, N Joschko, W Stremmel, M Müller-Schilling (2011) MicroRNAs are key players of the p53 pathway in hepatocellular carcinoma. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269523

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