CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Epigenetic and post-transcriptional mechanisms are responsible for disruption of the Hippo tumor suppressor pathway in human hepatocellular carcinoma
DOI 10.1055/s-0030-1269527
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Autor:innenDF Calvisi, X Chen, C Ho, S Ladu, G Destefanis, S Mattu, S Delogu, SS Thorgeirsson, F Dombrowski, M Evert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Mounting evidence indicates that disruption of the Hippo tumor suppressor pathway contributes to hepatocarcinogenesis. In this study, we investigated the expression levels of the members of the Hippo signaling in a collection of human hepatocellular carcinoma (HCC) as well as in in vivo and in vitro models. Thus, promoter and genomic status of Hippo pathway members were assessed in HCC by methylation and microsatell…
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Zitierempfehlung
DF Calvisi, X Chen, C Ho, S Ladu, G Destefanis, S Mattu, S Delogu, SS Thorgeirsson, F Dombrowski, M Evert (2011) Epigenetic and post-transcriptional mechanisms are responsible for disruption of the Hippo tumor suppressor pathway in human hepatocellular carcinoma. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269527
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