CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Activation of the SKP2 protooncogene is a common effector pathway in hepatocarcinogenesis and contributes to malignant transformation of the liver
DOI 10.1055/s-0030-1269529
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Autor:innenDF Calvisi, X Chen, C Ho, S Ladu, S Mattu, G Destefanis, S Delogu, F Dombrowski, M Evert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
We have recently shown that upregulation of SKP2 protooncogene is associated with the development and progression of human hepatocellular carcinoma (HCC). In the present study, we further investigated the functional role of SKP2 by using in vitro and in vivo approaches. Forced overexpression of a number of known liver oncogenes, including AKT, E2F1, N-Ras, ERK2, STAT5b, and mutated beta-catenin in human HCC cell lin…
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Zitierempfehlung
DF Calvisi, X Chen, C Ho, S Ladu, S Mattu, G Destefanis, S Delogu, F Dombrowski, M Evert (2011) Activation of the SKP2 protooncogene is a common effector pathway in hepatocarcinogenesis and contributes to malignant transformation of the liver. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269529
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