CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Role of TGF-β and Smad7 in apoptosis of HCC cells
DOI 10.1055/s-0030-1269538
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Fabian, J Dzieran, S Dooley, NM Meindl-Beinker
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
TGF-β plays a pivotal role in cell signaling in liver. In healthy tissue and early stages of liver diesease, TGF-β signaling controls apoptosis, cell proliferation and differentiation, thereby acting as a tumor suppressor. During tumor progression in hepatocellular carcinogenesis TGF-β acquires tumor promoting functions. For urgently needed treatment development it is essential to elucidate the point of decision, wh…
Zitieren
Zitierempfehlung
J Fabian, J Dzieran, S Dooley, NM Meindl-Beinker (2011) Role of TGF-β and Smad7 in apoptosis of HCC cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269538
Mit CareLit weiterarbeiten