CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hepcidin knockout mice as a model of iron-overload associated liver disease
DOI 10.1055/s-0030-1269571
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Autor:innenM Lunova, S Vaulont, J Haybaeck, K Lackner, G Adler, P Strnad
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: Hepcidin is the central regulator of iron homeostasis. Disrupted hepcidin signalling results in hereditary hemochromatosis and iron overload in chronic liver disorders. While the association between iron overload and development of end-stage liver disease is well established, our understanding of the underlying pathomechanisms is hampered by the lack of a suitable animal model. To circumvent thi…
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Zitierempfehlung
M Lunova, S Vaulont, J Haybaeck, K Lackner, G Adler, P Strnad (2011) Hepcidin knockout mice as a model of iron-overload associated liver disease. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269571
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