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Delta like ligand 4 expression in the endothelium of hepatocellular carcinoma is associated with poor tumor differentiation and early tumor stages

C Mogler, H Weng, S Singer, P Schirmacher, T Longerich · Zeitschrift für Gastroenterologie · Ausgabe 01/2011

DOI 10.1055/s-0030-1269578

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Autor:innenC Mogler, H Weng, S Singer, P Schirmacher, T Longerich
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben

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Aims: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Most tumors are stroma-poor but highly vascularised. Overexpression of the tip cell marker and Notch ligand delta like ligand 4 (DLL4) has been described in many tumor entities but not yet investigated in human HCCs. First attempts have been made to further characterize tumor vasculature, but to date no clear data exist about sprouting…

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C Mogler, H Weng, S Singer, P Schirmacher, T Longerich (2011) Delta like ligand 4 expression in the endothelium of hepatocellular carcinoma is associated with poor tumor differentiation and early tumor stages. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269578

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