CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Induction and siRNA-mediated downregulation of the lipid droplet-associated PAT-proteins adipophilin and TIP47 in cell culture models of hepatocyte steatosis
DOI 10.1055/s-0030-1269581
Bibliografische Angaben
Nachweis in CareLit
Autor:innenLM Pawella, BK Straub, M Hashani, P Schirmacher
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Hepatocellular lipid droplet (LD) accumulation is the most frequent liver pathology in western countries, and is caused by a broad range of disorders such as alcohol abuse and metabolic syndrome. The LD-surface is governed by amphiphilic proteins of the PAT-family (perilipin, adipophilin, TIP47;=PERILIPIN 1–3). Downregulation of adipophilin has been shown to inhibit diet-induced fatty liver in mice. For human liver,…
Zitieren
Zitierempfehlung
LM Pawella, BK Straub, M Hashani, P Schirmacher (2011) Induction and siRNA-mediated downregulation of the lipid droplet-associated PAT-proteins adipophilin and TIP47 in cell culture models of hepatocyte steatosis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269581
Mit CareLit weiterarbeiten