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The role of cytochrome P-4502E1 in the development of hepatic fat, fibrosis and DNA lesions in patients with of alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD)

H Qin, K Glassen, G Millonig, KB Linhart, H Bartsch, XD Wang, S Mueller, HK Seitz · Zeitschrift für Gastroenterologie · Ausgabe 01/2011

DOI 10.1055/s-0030-1269583

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Autor:innenH Qin, K Glassen, G Millonig, KB Linhart, H Bartsch, XD Wang, S Mueller, HK Seitz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben

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Aims: Although the pathogenesis of alcoholic liver disease (ALD) is still unclear, there is increasing evidence of the involvement of cytochrome P-4502E1 (CYP2E1) in its progression, since the inhibition of CYP2E1 in animal experiments prevents ALD. In addition, CYP2E1 seems also responsible for the generation of carcinogenic DNA lesions in both ALD and NAFLD. The purpose of this study was to further investigate the…

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H Qin, K Glassen, G Millonig, KB Linhart, H Bartsch, XD Wang, S Mueller, HK Seitz (2011) The role of cytochrome P-4502E1 in the development of hepatic fat, fibrosis and DNA lesions in patients with of alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD). Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269583

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