CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Darbepoetin inhibits proliferation of Huh-7 and Hep3B cells via up-regulation of the tumor-suppressor gene p53
DOI 10.1055/s-0030-1269599
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Autor:innenL Schyschka, J Neumann, R Mühl-Benninghaus, M Unger, U Stöckle, S Ehnert, A Nüssler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
In 2002 Aranesp (Darbepoetin) was licensed for patients with solid tumors suffering from chemotherapy-dependent anemia. As a better blood supply may favor tumor growth and spreading, we wanted to investigate whether there are direct effects of Darbepoetin on liver tumor cell lines or primary human hepatocytes. Human hepatoma cell-lines used were HepG2, Hep3B, SkHep1, Huh-7, AKN1, HCC-T and HCC-M. Primary human hepat…
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Zitierempfehlung
L Schyschka, J Neumann, R Mühl-Benninghaus, M Unger, U Stöckle, S Ehnert, A Nüssler (2011) Darbepoetin inhibits proliferation of Huh-7 and Hep3B cells via up-regulation of the tumor-suppressor gene p53. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269599
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