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Activin A resistant fetal liver stem/progenitor cells (FLSPC) vigorously repopulate aging rat liver through augmented cell competition

A Menthena, CI Koehler, JS Sandhu, MI Yovchev, E Hurston, DA Shafritz, M Oertel · Zeitschrift für Gastroenterologie · Ausgabe 01/2011

DOI 10.1055/s-0030-1269640

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Autor:innenA Menthena, CI Koehler, JS Sandhu, MI Yovchev, E Hurston, DA Shafritz, M Oertel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Recently, we showed that highly proliferative FLSPC repopulate the normal young recipient liver by out-competing less proliferative host hepatocytes (HC) by inducing their apoptosis. The aim of the study was to discover the mechanism through which FLSPC are capable to repopulate the recipient liver and more effectively repopulate the liver of aging rats. We observed a 4–5fold increase of liver repopulation after FLS…

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Zitierempfehlung

A Menthena, CI Koehler, JS Sandhu, MI Yovchev, E Hurston, DA Shafritz, M Oertel (2011) Activin A resistant fetal liver stem/progenitor cells (FLSPC) vigorously repopulate aging rat liver through augmented cell competition. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269640

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