CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Murine CD47 expressed on the surface of human hepatocytes protects from murine macrophage action in vitro and in vivo
DOI 10.1055/s-0030-1269650
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Autor:innenJ Waern, Q Yuan, M Ott, MP Manns, M Bock
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Macrophages play an important role in the rejection of transplanted xenogeneic cells. Recently, is has been shown that species-specific interaction between CD47 on target cells and SIRPα on macrophages inactivates macrophages and reduces phagocytosis. In this study we use lentiviral gene transfer to express murine CD47 in human cell lines to test whether they become less susceptible for phagocytosis by murine macrop…
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Zitierempfehlung
J Waern, Q Yuan, M Ott, MP Manns, M Bock (2011) Murine CD47 expressed on the surface of human hepatocytes protects from murine macrophage action in vitro and in vivo. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269650
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