CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Immune regulation in response to ConA-induced liver injury is mediated by regulatory T cells induced in dependence of IFNgamma
DOI 10.1055/s-0030-1269666
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Autor:innenB Claass, A Erhardt, G Tiegs
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: A sublethal dose of concanavalin A (ConA) induces tolerance towards ConA hepatitis in mice within one week. Tolerance is mediated by IL-10 producing Foxp3+ regulatory T cells (Tregs). This study is intended to elucidate the mechanism of the generation of tolerance mediating highly suppressive Tregs. Methods: The role of pro-inflammatory IFNγ in Treg priming and induction of ConA tolerance was investiga…
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Zitierempfehlung
B Claass, A Erhardt, G Tiegs (2011) Immune regulation in response to ConA-induced liver injury is mediated by regulatory T cells induced in dependence of IFNgamma. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269666
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