CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The common bile salt transporter polymorphism ABCB11C.1331T>C is associated with HCV infection but not with increased liver stiffness in a german cohort: Mechanistical implications
DOI 10.1055/s-0030-1269688
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Autor:innenR Müllenbach, S Weber, V Zimmer, M Krawczyk, F Lammert, F Grünhage
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The hepatocanalicular bile salt export pump BSEP (ABCB11) is the central transporter of bile acids from hepatocytes into bile canaliculi. Homozygous inactivations cause progressive familial cholestasis type 2 (PFIC2) resulting in end-stage liver disease, fibrosis and cirrhosis. The frequent sequence variant ABCB11 c.1331T>C (p.V444A) has been associated with different serum bile acid levels. Homozygosity for the [C]…
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Zitierempfehlung
R Müllenbach, S Weber, V Zimmer, M Krawczyk, F Lammert, F Grünhage (2011) The common bile salt transporter polymorphism ABCB11C.1331T>C is associated with HCV infection but not with increased liver stiffness in a german cohort: Mechanistical implications. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269688
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