CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism
DOI 10.1055/s-0030-1269694
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Autor:innenFA Schildberg, A Wojtalla, SV Siegmund, L Diehl, C Kurts, PA Knolle
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The role of the liver in induction of T cell tolerance is achieved by the action of tolerogenic hepatic antigen-presenting cells (APC) and regulatory T cells. Hepatic stellate cells (HSC) are known to have diverse immune functions ranging from immunogenic antigen presentation to induction of T cell apoptosis. Here we report on a novel role of stellate cells vetoing priming of naive CD8 T cells. Murine and human HSCs…
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Zitierempfehlung
FA Schildberg, A Wojtalla, SV Siegmund, L Diehl, C Kurts, PA Knolle (2011) Hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269694
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