CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The association of 2B4 up-regulation and SAP down-regulation indicates exhaustion of virus-specific CD8+ T cells
DOI 10.1055/s-0030-1269695
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Nachweis in CareLit
Autor:innenV Schlaphoff, S Lunemann, SV Pothakamuri, J Jaroszewicz, J Grabowski, S Pischke, FA Helfritz, MP Manns, M Cornberg, H Wedemeyer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The outcome of viral infections is dependent on the function of CD8+ T cells which are tightly regulated by costimulatory molecules. The NK cell receptor 2B4 (CD244) is a transmembrane protein belonging to the Ig superfamily which can also be expressed by CD8+ T cells. The aim of this study was to analyze the role of 2B4 as an additional costimulatory receptor regulating CD8+ T cell function and in particular to inv…
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Zitierempfehlung
V Schlaphoff, S Lunemann, SV Pothakamuri, J Jaroszewicz, J Grabowski, S Pischke, FA Helfritz, MP Manns, M Cornberg, H Wedemeyer (2011) The association of 2B4 up-regulation and SAP down-regulation indicates exhaustion of virus-specific CD8+ T cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269695
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