CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Strong in vivo antiviral efficacy of a new L-deoxycytidine derivate in hepatitis B virus infected chimeric uPA mice
DOI 10.1055/s-0030-1269702
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Autor:innenT Volz, L Allweiss, M Lütgehetmann, A Lohse, E Matthes, J Petersen, M Dandri
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Suppression of viral replication with nucleos(t)ide inhibitors has shown to greatly improve the outcome of chronic hepatitis B virus (HBV) infection. L-nucleoside analogues represent one of the most efficient groups of antiviral compounds. Previous studies showed that among these nucleosides, a novel L-hydroxydeoxycytidine compound, the ß-L-2´,3´-didehydro-2´,3´-dideoxy-N4-hydroxy-5-fluorocytidine (L-Hyd4FC) with an…
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Zitierempfehlung
T Volz, L Allweiss, M Lütgehetmann, A Lohse, E Matthes, J Petersen, M Dandri (2011) Strong in vivo antiviral efficacy of a new L-deoxycytidine derivate in hepatitis B virus infected chimeric uPA mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269702
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