CareLit · DOI-Nachweis · Klinische Pädiatrie
BH3 Profiling – A Predictive Biomarker for Apoptotic Response to Chemotherapy
DOI 10.1055/s-0030-1270302
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Letai
ZeitschriftKlinische Pädiatrie
Ausgabe12/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
During oncogenesis, cancer cells provoke death signals due to a variety of aberrant behaviors, including genomic instability, oncogene activation, and anoikis. In order to grow and persist as clinically relevant tumors, cancer cells must find a way to escape pro-death signals in the intrinsic or mitochondrial apoptotic pathway. We have developed a tool, BH3 profiling, which can detect how cancer cells evade apoptosi…
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Zitierempfehlung
A Letai (2010) BH3 Profiling – A Predictive Biomarker for Apoptotic Response to Chemotherapy. Klinische Pädiatrie (12). https://doi.org/10.1055/s-0030-1270302
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