CareLit · DOI-Nachweis · Klinische Pädiatrie
The "Ideal" Target's Network: Factors Modulating EWS-FLI1 Expression and Function in Ewing's Sarcoma
DOI 10.1055/s-0030-1270309
Bibliografische Angaben
Nachweis in CareLit
Autor:innenH Kovar, M Kauer, P Mesdagh, J Ban, S Niedan, G Jug, F Speleman, C Poremba, D Aryee
ZeitschriftKlinische Pädiatrie
Ausgabe12/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
EWS-FLI1 is a chimeric transcription factor that results from gene fusion as a consequence of chromosomal translocation exclusively in Ewing's sarcoma family tumors (ESFT). Recent genomic studies have identified a network of EWS-FLI1 regulated genes and functions. These studies mainly relied on experimentally modulating EWS-FLI1 expression in ESFT cell lines under standard in vitro growth conditions (21% oxygene, mo…
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Zitierempfehlung
H Kovar, M Kauer, P Mesdagh, J Ban, S Niedan, G Jug, F Speleman, C Poremba, D Aryee (2010) The "Ideal" Target's Network: Factors Modulating EWS-FLI1 Expression and Function in Ewing's Sarcoma. Klinische Pädiatrie (12). https://doi.org/10.1055/s-0030-1270309
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