CareLit · DOI-Nachweis · Klinische Pädiatrie
The Hedgehog Signaling Pathway as a Therapeutic Target in Pediatric Liver Tumors
DOI 10.1055/s-0030-1270312
Bibliografische Angaben
Nachweis in CareLit
Autor:innenR Kappler
ZeitschriftKlinische Pädiatrie
Ausgabe12/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Recent evidence has indicated that Hedgehog signaling significantly contributes to liver development and regeneration. However, constitutive activation of the pathway drives growth of liver tumors, both in adults and children. This talk will focus on strategies set up to block the Hedgehog signaling cascade on multiple levels. It will describe the current options to toggle the pathway by inhibiting transmembrane pro…
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Zitierempfehlung
R Kappler (2010) The Hedgehog Signaling Pathway as a Therapeutic Target in Pediatric Liver Tumors. Klinische Pädiatrie (12). https://doi.org/10.1055/s-0030-1270312
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