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Single-cell Phospho-Profiling in Pediatric B-cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Reveals Signaling Differences in Cytogenetic and Prognostic Subgroups

M Queudeville, SM Eckhoff, KM Debatin, LH Meyer · Klinische Pädiatrie · Ausgabe 12/2010

DOI 10.1055/s-0030-1270332

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Autor:innenM Queudeville, SM Eckhoff, KM Debatin, LH Meyer
ZeitschriftKlinische Pädiatrie
Ausgabe12/2010
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Reasons for poor response to therapy and/or relapse in pediatric ALL remain poorly understood, especially in patients originally stratified into low-risk groups. As it is widely known that oncogenesis and tumor progression are supported by alterations in cellular signaling, we analyzed 22 primary xenografted BCP- ALL samples in respect to their potential to react to a given stimulus in vitro and related the phosphor…

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Zitierempfehlung

M Queudeville, SM Eckhoff, KM Debatin, LH Meyer (2010) Single-cell Phospho-Profiling in Pediatric B-cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Reveals Signaling Differences in Cytogenetic and Prognostic Subgroups. Klinische Pädiatrie (12). https://doi.org/10.1055/s-0030-1270332

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