CareLit · DOI-Nachweis · Pneumologie
Gp120 reduces AHR and airway inflammation in a humanized mouse model of allergic asthma through activation of regulatory T cells
DOI 10.1055/s-0030-1270356
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Nachweis in CareLit
Autor:innenH Martin, S Reuter, N Dehzad, A Heinz, I Bellinghausen, S Korn, J Saloga, C Becker, R Buhl, C Taube
ZeitschriftPneumologie
Ausgabe02/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Within this study we established a humanized mouse model of allergic asthma in immune deficient NOD-Scid gc–/– mice. For reconstitution of the animals we transferred 5 million peripheral blood mononuclear cells (PBMC) from allergic donors with sensitization against birch pollen intraperitoneally. The injection of PBMC together with birch and IL-4 followed by intranasal allergen challenge increased airway hyperrespon…
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Zitierempfehlung
H Martin, S Reuter, N Dehzad, A Heinz, I Bellinghausen, S Korn, J Saloga, C Becker, R Buhl, C Taube (2011) Gp120 reduces AHR and airway inflammation in a humanized mouse model of allergic asthma through activation of regulatory T cells. Pneumologie (02). https://doi.org/10.1055/s-0030-1270356
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