CareLit · DOI-Nachweis · Pneumologie
Cathepsin G and neutrophil elastase play critical and non-redundant roles in lung protective immunity against S. pneumoniae in mice
DOI 10.1055/s-0030-1270362
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Nachweis in CareLit
Autor:innenI Hahn, A Klaus, K Steinwede, N Ding, J Bohling, F Gauthier, T Welte, UA Maus
ZeitschriftPneumologie
Ausgabe02/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Neutrophil serine proteases cathepsin G (CtsG), neutrophil elastase (NE) and proteinase-3 (PR3) have recently been shown to contribute to killing of Streptococcus pneumoniae in vitro. However, their relevance in lung protective immunity against different serotypes of S. pneumoniae in vivo has not been determined so far. We here infected CtsG-deficient mice and CtsG/NE deficient mice with two serotypes of S. pneumoni…
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Zitierempfehlung
I Hahn, A Klaus, K Steinwede, N Ding, J Bohling, F Gauthier, T Welte, UA Maus (2011) Cathepsin G and neutrophil elastase play critical and non-redundant roles in lung protective immunity against S. pneumoniae in mice. Pneumologie (02). https://doi.org/10.1055/s-0030-1270362
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