CareLit · DOI-Nachweis · Pneumologie
STING and IRF3 mediate cytosolic innate immune recognition of Streptococcus pneumoniae
DOI 10.1055/s-0030-1270370
Bibliografische Angaben
Nachweis in CareLit
Autor:innenU Koppe, S Bauer, M Witzenrath, N Suttorp, B Opitz
ZeitschriftPneumologie
Ausgabe02/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Streptococcus pneumoniae is a leading cause of community-acquired pneumonia and sepsis world-wide. The innate immune system detects S. pneumoniae through pattern-recognition receptors including Toll-like receptors (TLRs) and NOD-like receptors (NLRs). In this project, we examine an additional innate immune recognition pathway sensing pneumococcal infection. We found that both murine and human alveolar macrophages pr…
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Zitierempfehlung
U Koppe, S Bauer, M Witzenrath, N Suttorp, B Opitz (2011) STING and IRF3 mediate cytosolic innate immune recognition of Streptococcus pneumoniae. Pneumologie (02). https://doi.org/10.1055/s-0030-1270370
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