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Resting Aspergillus fumigatus conidia induce IFN-β signaling in respiratory epithelial cells

C Beisswenger, C Hess, R Bals · Pneumologie · Ausgabe 02/2011

DOI 10.1055/s-0030-1270371

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Autor:innenC Beisswenger, C Hess, R Bals
ZeitschriftPneumologie
Ausgabe02/2011
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Aspergillus fumigatus is a fungal pathogen of major clinical importance. However, little is known about the role of human bronchial epithelial cells (HBEC) during A. fumigatus conidia induced inflammation. Here we show that differentiated respiratory epithelial cells recognize resting but not swollen conidia or hyphae resulting in the induction of the IFN-β signaling pathway and the expression of IFN-β inducible gen…

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Zitierempfehlung

C Beisswenger, C Hess, R Bals (2011) Resting Aspergillus fumigatus conidia induce IFN-β signaling in respiratory epithelial cells. Pneumologie (02). https://doi.org/10.1055/s-0030-1270371

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