CareLit · DOI-Nachweis · Pneumologie
Inhalative use of the endolysin Cpl-1 rescues mice with fatal pneumococcal pneumonia
DOI 10.1055/s-0030-1270372
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJM Doehn, K Reppe, B Gutbier, T Tschernig, A Hocke, VA Fischetti, N Suttorp, S Hippenstiel, M Witzenrath
ZeitschriftPneumologie
Ausgabe02/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objectives: Community-acquired pneumonia (CAP) is associated with considerable morbidity and mortality. S. pneumoniae remains the most common cause in pneumonia and pneumococcal resistance to multiple antibiotics is increasing. The purified bacteriophage endolysin Cpl-1 rapidly and specifically kills pneumococci on contact. We have recently shown that repetitive intraperitoneal injections with Cpl-1 rescued mice wit…
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Zitierempfehlung
JM Doehn, K Reppe, B Gutbier, T Tschernig, A Hocke, VA Fischetti, N Suttorp, S Hippenstiel, M Witzenrath (2011) Inhalative use of the endolysin Cpl-1 rescues mice with fatal pneumococcal pneumonia. Pneumologie (02). https://doi.org/10.1055/s-0030-1270372
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