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The role of human airway smooth muscle cells in chronic airway inflammation and putative therapeutic potential of endothelin receptor antagonism

J Knobloch, Y Lin, D Jungck, K Urban, J Strauch, E Stoelben, A Koch · Pneumologie · Ausgabe 02/2011

DOI 10.1055/s-0030-1270381

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Autor:innenJ Knobloch, Y Lin, D Jungck, K Urban, J Strauch, E Stoelben, A Koch
ZeitschriftPneumologie
Ausgabe02/2011
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: TNFα has a key role in the establishment of chronic airway inflammation. TNFα-induced expression of inflammatory genes might depend on the vasoconstrictor endothelin-1 (ET-1) [Thorax, 2009, 64:1044–1052]. Objective: We aimed to investigate the role of human airway smooth muscle cells (HASMCs) in the establishment of chronic airway inflammation. We further elucidated the anti-inflammatory properties of th…

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Zitierempfehlung

J Knobloch, Y Lin, D Jungck, K Urban, J Strauch, E Stoelben, A Koch (2011) The role of human airway smooth muscle cells in chronic airway inflammation and putative therapeutic potential of endothelin receptor antagonism. Pneumologie (02). https://doi.org/10.1055/s-0030-1270381

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