CareLit · DOI-Nachweis · Pneumologie
Up-regulated expression of immunoproteasome subunit LMP7 in alveolar macrophages of hypersensitivity pneumonitis
DOI 10.1055/s-0031-1271995
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Cai, S Sixt, F Bonella, T Anlasik, T Mori, J Guzman, U Costabel
ZeitschriftPneumologie
Ausgabe03/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Proteasomes are important proteolytic complexes for the processing of endogenous antigen presentation by major histocompatibility complex (MHC) class I molecules. Low molecule weight protein (LMP) 2 and LMP7 are IFN-γ-inducible and MHC-II-encoded β subunits which can incorporate into the constitutive 20S proteasome and turn it to immunoproteasomes with alterations of catalytic properties. Aim of the stud…
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Zitierempfehlung
M Cai, S Sixt, F Bonella, T Anlasik, T Mori, J Guzman, U Costabel (2011) Up-regulated expression of immunoproteasome subunit LMP7 in alveolar macrophages of hypersensitivity pneumonitis. Pneumologie (03). https://doi.org/10.1055/s-0031-1271995
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