CareLit · DOI-Nachweis · Pneumologie
The effect of endothelin-1 on human basophil function in vitro
DOI 10.1055/s-0031-1272049
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Cima, S Blunder, S Desole, J Günther, C Kähler
ZeitschriftPneumologie
Ausgabe03/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Endothelin-1 (ET-1) has proinflammatory properties and contributes to allergic late-phase responses. As basophils play a key role in allergic rhinitis or asthma, we investigated the effect of ET-1 on basophils. Cells were isolated from venous blood of healthy donors via magnetic cell sorting (MACS®). Basophils migrated towards ET-1 [10–6-10–16 M] or MCP-1 [10–8 M] (positive control) for 90min in modified Boyden cham…
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Zitierempfehlung
K Cima, S Blunder, S Desole, J Günther, C Kähler (2011) The effect of endothelin-1 on human basophil function in vitro. Pneumologie (03). https://doi.org/10.1055/s-0031-1272049
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