CareLit · DOI-Nachweis · Pneumologie
Terguride attenuates myocardial remodelling and diastolic dysfunction in the pressure overloaded right heart
DOI 10.1055/s-0031-1272119
Bibliografische Angaben
Nachweis in CareLit
Autor:innenDR Krompiec, W Janssen, S Savai Pullamsetti, Y Schymura, H Luitel, HA Ghofrani, N Weissmann, F Grimminger, R Reiter, W Seeger, RT Schermuly
ZeitschriftPneumologie
Ausgabe03/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Rationale: Sustained right ventricular (RV) pressure overload causes myocardial remodelling and heart failure. However, little is known about the role of serotonin (5-hydroxytryptamine, 5-HT) and its receptors in RV hypertrophy due to RV pressure overload. We therefore investigated the effects of the 5-HT2a- and 5-HT2b-receptor antagonist terguride on myocardial hypertrophy and fibrosis, as well as diastolic functio…
Zitieren
Zitierempfehlung
DR Krompiec, W Janssen, S Savai Pullamsetti, Y Schymura, H Luitel, HA Ghofrani, N Weissmann, F Grimminger, R Reiter, W Seeger, RT Schermuly (2011) Terguride attenuates myocardial remodelling and diastolic dysfunction in the pressure overloaded right heart. Pneumologie (03). https://doi.org/10.1055/s-0031-1272119
Mit CareLit weiterarbeiten