CareLit · DOI-Nachweis · Klinische Neurophysiologie
PET/MRI-based phenotyping of a transgenic rat model for Huntington's disease – a 16 months follow-up study
DOI 10.1055/s-0031-1272762
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Nachweis in CareLit
Autor:innenE. Hölzner, V. Lippross, S. Hermann, N. Nagelmann, J. Heselhaus, S. Bohlen, H. Kugel, M. Deppe, J. Sommer, C. Bremer, H. Nguyen, O. Riess, S. von Hörsten, M. Schäfers, A.H. Jacobs, R. Reilmann
ZeitschriftKlinische Neurophysiologie
Ausgabe03/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: The tgHD rat (von Horsten et al. 2003) carries 51 CAG repeats, which is within ranges observed in human genotypes. It was previously reported that small animal FDG-PET is able to detect hypometabolism in the whole brain of tgHD rats at 18–24 months of age. However, this initial imaging study was limited by its cross-sectional nature, the resolution of the small animal PET employed and the lack of a regio…
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Zitierempfehlung
E. Hölzner, V. Lippross, S. Hermann, N. Nagelmann, J. Heselhaus, S. Bohlen, H. Kugel, M. Deppe, J. Sommer, C. Bremer, H. Nguyen, O. Riess, S. von Hörsten, M. Schäfers, A.H. Jacobs, R. Reilmann (2011) PET/MRI-based phenotyping of a transgenic rat model for Huntington's disease – a 16 months follow-up study. Klinische Neurophysiologie (03). https://doi.org/10.1055/s-0031-1272762
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