CareLit · DOI-Nachweis · Klinische Neurophysiologie
Multi-tracer microPET imaging of a mouse model of Alzheimer's disease to assess microglial activation and anti-inflammatory treatment
DOI 10.1055/s-0031-1272776
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS. Rapic, H. Backes, T. Viel, P. Monfared, B. Neumaier, S. Vollmar, M. Hoehn, A. Van der Linden, M.T. Heneka, A.H. Jacobs
ZeitschriftKlinische Neurophysiologie
Ausgabe03/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: In Alzheimer's disease (AD), activated microglia play an important role in amyloid clearance and secretion of pro-inflammatory molecules that lead to chronic neuroinflammation. The nuclear peroxisome proliferator-activated receptor γ (PPAR-g) is involved in the regulation of inflammatory processes at transcriptional level. Aim: To determine whether microglial activation as assessed by micro-positron em…
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Zitierempfehlung
S. Rapic, H. Backes, T. Viel, P. Monfared, B. Neumaier, S. Vollmar, M. Hoehn, A. Van der Linden, M.T. Heneka, A.H. Jacobs (2011) Multi-tracer microPET imaging of a mouse model of Alzheimer's disease to assess microglial activation and anti-inflammatory treatment. Klinische Neurophysiologie (03). https://doi.org/10.1055/s-0031-1272776
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