CareLit · DOI-Nachweis · Klinische Pädiatrie
Atypical Hemolytic Uremic Syndrome (aHUS): Mutations in components of complement and their impact on the clinical course
DOI 10.1055/s-0031-1273833
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Nachweis in CareLit
Autor:innenN Bachmann, A Melk, B Kranz, H Fehrenbach, N Wirtz, K Häffner, L Pape, C Bergmann
ZeitschriftKlinische Pädiatrie
Ausgabe03/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Hemolytic uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia, and renal impairment, and is the most common cause of acute renal failure in childhood. Most cases occur secondary to infection with Shiga toxin-producing bacteria. About 10% of HUS patients are classified as atypical (aHUS) with a generally poorer prognosis. Genetic complement abnormalities play a major role in aHUS and lead to…
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Zitierempfehlung
N Bachmann, A Melk, B Kranz, H Fehrenbach, N Wirtz, K Häffner, L Pape, C Bergmann (2011) Atypical Hemolytic Uremic Syndrome (aHUS): Mutations in components of complement and their impact on the clinical course. Klinische Pädiatrie (03). https://doi.org/10.1055/s-0031-1273833
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