CareLit · DOI-Nachweis · Klinische Pädiatrie
IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol
DOI 10.1055/s-0031-1277064
Bibliografische Angaben
Nachweis in CareLit
Autor:innenP Breithaupt, B Meissner, M Zimmermann, A Möricke, A Schrauder, J Harbott, WD Ludwig, R Köhler, CR Bartram, M Schrappe, G Cario, M Stanulla
ZeitschriftKlinische Pädiatrie
Ausgabe05/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Alteration of the IKZF1 gene has been associated with a poor outcome in pediatric precursor B-cell acute lymphoblastic leukemia (ALL). Method: To assess the prognostic value of IKZF1 deletions we screened a representative cohort of 409 pediatric ALL patients treated on the German ALL-BFM 2000 study protocol, by multiplex ligation-dependent probe amplification (MLPA). Results: Patients with IKZF1 deleti…
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Zitierempfehlung
P Breithaupt, B Meissner, M Zimmermann, A Möricke, A Schrauder, J Harbott, WD Ludwig, R Köhler, CR Bartram, M Schrappe, G Cario, M Stanulla (2011) IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0031-1277064
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