CareLit · DOI-Nachweis · Klinische Pädiatrie
Molecular characterization of a new anti-idiotype antibody for active immunotherapy in neuroblastoma
DOI 10.1055/s-0031-1277069
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Schmidt, N Siebert, HN Lode
ZeitschriftKlinische Pädiatrie
Ausgabe05/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Glycolipid Disialoganglioside GD2 is a highly expressed but poorly immunogenic antigen in neuroblastoma (NB). An anti-idiotype antibody (AIT-ab), which mimics the paratope of GD2, could induce an active immune response against NB. Methods/Results: We developed a new AIT-ab called Ganglidiomab by immunizing BALB/c mice with murine ab 14G2A. Hybridomas were generated and clones secreting AIT-ab were iden…
Zitieren
Zitierempfehlung
M Schmidt, N Siebert, HN Lode (2011) Molecular characterization of a new anti-idiotype antibody for active immunotherapy in neuroblastoma. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0031-1277069
Mit CareLit weiterarbeiten