CareLit · DOI-Nachweis · Klinische Pädiatrie
Screening for the P2RY8-CRLF2 fusion gene in childhood acute lymphoblastic leukaemia
DOI 10.1055/s-0031-1277073
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Autor:innenM Morak, R Joas, S Fischer, A Attarbaschi, G Mann, R Panzer-Grümayer
ZeitschriftKlinische Pädiatrie
Ausgabe05/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Childhood acute lymphoblastic leukaemia (ALL) is a heterogeneous disease characterized by a variety of genetic aberrations. Recently, a novel chromosomal rearrangement between P2RY8 and CRLF2 has been described in B-cell precursor (BCP) ALL. The P2RY8-CRLF2 fusion has been implicated in leukaemia development and appears to be associated with poor treatment outcome. In order to confirm the relevance of P2RY8-CRLF2 in…
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Zitierempfehlung
M Morak, R Joas, S Fischer, A Attarbaschi, G Mann, R Panzer-Grümayer (2011) Screening for the P2RY8-CRLF2 fusion gene in childhood acute lymphoblastic leukaemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0031-1277073
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