CareLit · DOI-Nachweis · Klinische Pädiatrie
GATA1s exerts fetal stage-specific oncogenic effects in hematopoietic stem and progenitor cells
DOI 10.1055/s-0031-1277089
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Nachweis in CareLit
Autor:innenA Maroz, C Hennig, D Reinhardt, JH Klusmann
ZeitschriftKlinische Pädiatrie
Ausgabe05/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Mutations of the hematopoietic transcription factor GATA1, leading to expression of a shorter N-terminal truncated protein (GATA1s) are associated with transient leukemia (TL) and acute megakaryoblastic leukemia (AMKL) in children with Down syndrome. However, the consequences of GATA1s expression in synergy with fetal background in human hematopoietic stem and progenitor cells (HSPCs) remain unknown. M…
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Zitierempfehlung
A Maroz, C Hennig, D Reinhardt, JH Klusmann (2011) GATA1s exerts fetal stage-specific oncogenic effects in hematopoietic stem and progenitor cells. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0031-1277089
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