CareLit · DOI-Nachweis · Klinische Pädiatrie
Partial or multi drug resistant NB cell lines are highly sensitive towards chimeric receptor expressing NK-92-scFv(ch14.18)-zeta
DOI 10.1055/s-0031-1277096
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Seidel, A Shibina, CP Reynolds, WS Wels, HN Lode, N Huebener
ZeitschriftKlinische Pädiatrie
Ausgabe05/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: The treatment of high-risk NB patients is still challenging, due to partial or multi-drug resistance (MDR) in relapsed tumors. Therefore we investigated the efficacy of GD2-specific NK-92 (NK-92tr) towards relapse NB cell lines. Aims and Methods: We compared cell lines established at time point of diagnosis with their respective relapse cell line in Cr51 release cytotoxicity assays. GD2 expression on c…
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Zitierempfehlung
D Seidel, A Shibina, CP Reynolds, WS Wels, HN Lode, N Huebener (2011) Partial or multi drug resistant NB cell lines are highly sensitive towards chimeric receptor expressing NK-92-scFv(ch14.18)-zeta. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0031-1277096
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