CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Bidirectional granule turnover in the submembrane space during K+ depolarization-induced secretion
DOI 10.1055/s-0031-1277280
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Autor:innenK Hatlapatka, M Matz, K Baumann, I Rustenbeck
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: The release of a pool of membrane-adjacent secretory granules which are in a primed and docked state and await one final trigger, a depolarization-induced influx of Ca2+, is held responsible for the first phase of glucose-induced insulin secretion. A number of recent observations has put this hypothesis into question. Methods: Insulin secretion was measured by perifusion of mouse islets and MIN6…
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Zitierempfehlung
K Hatlapatka, M Matz, K Baumann, I Rustenbeck (2011) Bidirectional granule turnover in the submembrane space during K+ depolarization-induced secretion. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0031-1277280
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