CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Potential mechanism of rosiglitazone induced myocellular insulin sensitivity-effects of rosiglitazone on 11β-hydroxysteroid dehydrogenase type 1 expression in skeletal muscle
DOI 10.1055/s-0031-1277365
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Mai, S Meinus, A Assmann, T Bobbert, J Andres, K Biedasek, C Maser-Gluth, S Wudy, M Hartmann, A Pfeiffer, S Diederich, J Spranger
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: PPARg agonists like rosiglitazone (R) increase insulin sensitivity in skeletal muscle, although the underlying mechanism is not entirely clear yet. The detrimental metabolic effects of glucocorticoids and 11β-HSD1 in human adipose tissue are well established, while data on myocellular 11β-HSD1 in humans are currently sparse. We aimed to investigate whether PPARg agonists modulate activity and expression of 11β…
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Zitierempfehlung
K Mai, S Meinus, A Assmann, T Bobbert, J Andres, K Biedasek, C Maser-Gluth, S Wudy, M Hartmann, A Pfeiffer, S Diederich, J Spranger (2011) Potential mechanism of rosiglitazone induced myocellular insulin sensitivity-effects of rosiglitazone on 11β-hydroxysteroid dehydrogenase type 1 expression in skeletal muscle. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0031-1277365
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