CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Dis-coordinated activation of de novo lipogenesis and stearoyl-CoA desaturase by monosaccharides determines liver fat accumulation in humans
DOI 10.1055/s-0031-1277376
Bibliografische Angaben
Nachweis in CareLit
Autor:innenG Silbernagel, M Kovarova, A Cegan, J Machann, S Unmuth, F Schick, N Stefan, HU Häring, E Schleicher, A Fritsche, A Peter
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Increased hepatic de novo lipogenesis of fatty acids has been implicated in the pathophysiology of fatty liver, potentially due to lipotoxic effects of the generated saturated fatty acids. Activation of fatty acid desaturation by stearoyl-CoA desaturase (SCD1) in parallel with lipogenesis may prevent lipotoxic effects and protect from hepatic steatosis. Methods: 20 healthy subjects (female/male 8/12, age 30.5±…
Zitieren
Zitierempfehlung
G Silbernagel, M Kovarova, A Cegan, J Machann, S Unmuth, F Schick, N Stefan, HU Häring, E Schleicher, A Fritsche, A Peter (2011) Dis-coordinated activation of de novo lipogenesis and stearoyl-CoA desaturase by monosaccharides determines liver fat accumulation in humans. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0031-1277376
Mit CareLit weiterarbeiten