CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Fecal supernatants from constipated IBS patients increase colonic permeability in mice by occludin degradation linked to cysteine-protease activity
DOI 10.1055/s-0031-1278432
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Annaházi, R Róka, M Leveque, H Eutamene, L Ferrier, K Gecse, A Rosztóczy, O Inczefi, G Ollé, F Izbéki, T Molnár, T Piche, V Theodorou, T Wittmann, L Bueno
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: Increased gut permeability has been described in all IBS subgroups. We have previously shown that fecal cysteine-protease (CP) activity is elevated only in constipated IBS (IBS-C) patients among IBS subtypes. Since CPs are involved in the increase of airway permeability by digesting tight junction proteins, we evaluated the ability of CP in the IBS-C fecal supernatant (FSN) to increase permeabil…
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Zitierempfehlung
A Annaházi, R Róka, M Leveque, H Eutamene, L Ferrier, K Gecse, A Rosztóczy, O Inczefi, G Ollé, F Izbéki, T Molnár, T Piche, V Theodorou, T Wittmann, L Bueno (2011) Fecal supernatants from constipated IBS patients increase colonic permeability in mice by occludin degradation linked to cysteine-protease activity. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0031-1278432
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