CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Screening of drug metabolizing capacity of the liver using peripheral blood sample. CYP-phenotype, allele and genotype frequencies
DOI 10.1055/s-0031-1278474
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Nachweis in CareLit
Autor:innenL Kóbori, E Sárváry, Z Gerlei, J Fazakas, A Doros, D Görög, I Fehérvári, B Nemes, M Temesvári, P Porrogi, J Paulik, K Monostory
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2011
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Drug-metabolizing capacity of the liver or transplanted liver graft depends on levels and activities of cytochrome P450 enzymes (CYP). Liver injury increase the morbidity and mortality rate after liver surgery or transplantation. Inter-individual variations in CYP genes result in differences in drug metabolism. Metabolomic and transcriptomic tools were used for CYP-phenotyping, based on the fact that strong correlat…
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Zitierempfehlung
L Kóbori, E Sárváry, Z Gerlei, J Fazakas, A Doros, D Görög, I Fehérvári, B Nemes, M Temesvári, P Porrogi, J Paulik, K Monostory (2011) Screening of drug metabolizing capacity of the liver using peripheral blood sample. CYP-phenotype, allele and genotype frequencies. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0031-1278474
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