CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The increased frequency of epithelial to myofibroblast transition during colorectal adenoma-dysplasia-carcinoma sequence
DOI 10.1055/s-0031-1278523
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Autor:innenG Valcz, T Krenács, F Sipos, A Kalmár, K Leiszter, J Molnár, B Molnár, Z Tulassay
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2011
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: The epithelial to myofibroblast transition (EMyT) is fundamental in the building of abnormal stromal microenvironment of colorectal cancer (CRC). The main regulator of EMyT is transforming growth factor (TGF)-β via its receptor (TGF-βRII) activation. During adenoma-dysplasia-carcinoma sequence (ADCS) the enhanced stromal TGF-β level may associate with Toll-like receptor (TLR)-9 activation by increased…
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Zitierempfehlung
G Valcz, T Krenács, F Sipos, A Kalmár, K Leiszter, J Molnár, B Molnár, Z Tulassay (2011) The increased frequency of epithelial to myofibroblast transition during colorectal adenoma-dysplasia-carcinoma sequence. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0031-1278523
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