CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The systemic iron hormone hepcidin is induced in macrophages by reactive oxygen species and during phagocytosis of oxidized erythrocytes
DOI 10.1055/s-0031-1285170
Bibliografische Angaben
Nachweis in CareLit
Autor:innenG Millonig, T Peccerella, HK Seitz, S Mueller
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: The peptide and liver-secreted hormone hepcidin is the master regulator of the body iron metabolism. It is secreted in response to elevated body iron stores or inflammatory conditions (IL-6). By blocking the iron exporter ferroportin, hepcidin not only prevents intestinal iron uptake but also iron release from macrophages that efficiently recycle iron by phagocytosing and degrading aged red blood cells (…
Zitieren
Zitierempfehlung
G Millonig, T Peccerella, HK Seitz, S Mueller (2011) The systemic iron hormone hepcidin is induced in macrophages by reactive oxygen species and during phagocytosis of oxidized erythrocytes. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0031-1285170
Mit CareLit weiterarbeiten