CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
A Loss of Smad2 dependent TGF-beta signaling correlates with poor differentiation in gastric cancer
DOI 10.1055/s-0031-1285287
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Nachweis in CareLit
Autor:innenH Weng, Y Wu, Q Li, J Yu, Y Mu, Y Liu, C Xu, Z Shen, Y Li, M Ebert, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: TGF-beta plays dual roles in progression of human cancer. In precancerous stages, TGF-beta acts as tumor suppressor by providing cytostatic downstream signaling, whereas in late cancer stages, it induces processes that support tumor progression, including stroma fibroblast activation, epithelial mesenchymal transition and metastasis. Due to the high complexity of the TGF-beta signaling pathway, molecular…
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Zitierempfehlung
H Weng, Y Wu, Q Li, J Yu, Y Mu, Y Liu, C Xu, Z Shen, Y Li, M Ebert, S Dooley (2011) A Loss of Smad2 dependent TGF-beta signaling correlates with poor differentiation in gastric cancer. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0031-1285287
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