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Inhibition of PDGFRβ in colorectal cancer cells leads to decreased proliferation and G2 cell cycle arrest

H Seemann, S Kaulfuss, R Dressel, P Burfeind, JG Scharf · Zeitschrift für Gastroenterologie · Ausgabe 08/2011

DOI 10.1055/s-0031-1285395

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Autor:innenH Seemann, S Kaulfuss, R Dressel, P Burfeind, JG Scharf
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2011
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the western world and growth factors and their receptors play a significant role in the regulation of CRC growth, angiogenesis, and metastasis. The platelet-derived growth factor receptor (PDGFR) has attracted increasing attention as potential target of anti-tumor therapy in CRC. In the present study the influence of the α- and β-subunit…

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Zitierempfehlung

H Seemann, S Kaulfuss, R Dressel, P Burfeind, JG Scharf (2011) Inhibition of PDGFRβ in colorectal cancer cells leads to decreased proliferation and G2 cell cycle arrest. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0031-1285395

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